Released on = September 5, 2006, 11:50 am

Press Release Author = Neil Watson

Industry = Biotech

Press Release Summary = PREMIER Biosoft International today announced the world wide
release of version 6 of Beacon Designer with support for MethyLight assays. Beacon
Designer is the only tool available for most of the popular real time PCR
chemistries such as SYBR® Green, TaqMan®, molecular beacon and FRET

Press Release Body = Palo Alto, California--August 31, 2006, PREMIER Biosoft
International today announced the world wide release of version 6 of Beacon
Designer, the only tool available for most of the popular real time PCR chemistries
such as SYBR® Green, TaqMan®, molecular beacon and FRET. Version 6 includes support
for MethyLight assays.

MethyLight assay, a TaqMan® probe based technique, can be effectively used for DNA
methylation profiling, measuring DNA methylation or detecting methylated alleles in
presence of the non-methylated ones. Due to the specificity of TaqMan® based assays,
it is much more accurate than an end point detection assay such as methyl specific
PCR (MSP).

\"With the release of Beacon Designer Version 6, PREMIER Biosoft International has
taken a step further in making a comprehensive, sophisticated and powerful real time
PCR oligo design tool available to thousands of labs all over the world,\" says Kay
Brown, V.P. Business Development and Marketing. \" We are proud to have organizations
such as NIH, FDA, CDC, USDA, Pfizer, Eli Lilly and Unilever as our customers.\"

Beacon Designer designs oligos for SYBR® Green, TaqMan®, LNAT spiked TaqMan®,
MethyLight, molecular beacon, NASBA® and FRET assays. Beacon Designer also enables
the design of compatible probes for proven SYBR® Green assays, resulting in cost
saving.

The most notable feature of Beacon Designer is the use of innovative and
sophisticated algorithms to ensure assay success. Primers are designed avoiding
regions of significant homology, identified by automatically interpreting BLAST
search results. Primer efficiency is enhanced by designing them in
template-structure-free regions. For multiplexing, Beacon Designer screens millions
of primer probe combinations to design primer probe sets for single tube multiplex
reactions. Whether the need is to incorporate well-proven sets for some of the
templates, or include reference or housekeeping genes for normalization purposes in
the assay, Beacon Designer is fully equipped.
For details, please visit: http://www.premierbiosoft.com/molecular_beacons/index.html

About PREMIER Biosoft International:
Founded in 1994, the company is a group of computer scientists and molecular
biologists dedicated to producing cutting edge intuitive software for the molecular
biologist. The goal of the company is to study the most recent innovations in
molecular biology and translate them into software products that aid biologists.
Additional information about PREMIER Biosoft International can be found at
http://www.PremierBiosoft.com

Contact:
Arun Apte
PREMIER Biosoft International
650-856-2703
http://www.PremierBiosoft.com



Web Site = http://www.premierbiosoft.com

Contact Details = 3786 Corina Way, Palo Alto, CA 94303-4504 USA
Tel: 650-856-2703 Fax: 650-618-1773
support@premierbiosoft.com